A New Weapon Against Cancer: Melitten (synthetic bee venom)

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After reading quite a few – and interesting – articles on melitten (a.k.a. as melittin), it seems that synthetic bee venom may have what it takes to take the fight against cancer to a new level, which is excellent news.

Here’s a short bibliography regarding melitten and its potential uses…

Jo, M. et al. Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells through induction of death receptors and inhibition of JAK2/STAT3 pathway. Chungbuk: College of Pharmacy and Medical Research Center, 2012. Abstract retrieved May 2013 from http://www.ncbi.nlm.nih.gov/pubmed/22027265.

National Cancer Institute. Tiny “Nanobee” Particles Deliver Cell-Killing Bee Toxin to Tumors in Mice. Retrieved May 2013 from http://www.cancer.gov/aboutnci/servingpeople/cancer-research-progress/advances/nanobees.

Park, J.W. et al. Effects of sweet bee venom pharmacopuncture treatment for chemotherapy-induced peripheral neuropathy: a case series. Daejeon: Daejeon University, 2012. Abstract retrieved May 2013 from http://www.ncbi.nlm.nih.gov/pubmed/21715371.

Phys.org (2009). Tumors feel the deadly sting of nanobees. Retrieved May 2013 from http://phys.org/news169150957.html.

Soman, N.R. et al. Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth. St. Louis: Washington University School of Medicine, 2009. Abstract retrieved May 2013 from http://www.ncbi.nlm.nih.gov/pubmed/19726870.

Vick, J.A. et al. Effect of bee venom and melittin on plasma cortisol in the unanesthetized monkey. Abstract retrieved from http://www.sciencedirect.com/science/article/pii/0041010172901195.

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